Wednesday, October 31, 2012

PVH to buy Warnaco for $2.9B, gain Calvin control

PVH Corp., whose brands include Calvin Klein and Tommy Hilfiger, has agreed to buy rival clothier The Warnaco Group Inc. in a cash-and-stock deal worth about $2.9 billion. The deal would create one of the world's largest clothing companies and cement PVH's control of the Calvin Klein clothing brand.

Warnaco already sells Calvin Klein jeans and underwear, the brand's two largest categories, under a license and also sells brands such as Speedo, Warner's and Olga.

The deal is the second big acquisition in three years for PVH, formerly known as Phillips Van Heusen. PVH acquired Tommy Hilfiger in 2010 for $3 billion.

Both companies' stock prices got a big boost from the deal. PVH's shares jumped $17.31, or 19 percent, to $108.81 in morning trading while Warnaco shares rose $20.01, or 39 percent, to $70.90.

PVH said Wednesday it will pay Warnaco shareholders $51.75 in cash and a portion of its stock for each Warnaco share. That puts the total per-share value at $68.43, a 34 percent premium over the company's closing price on Friday, the last day markets were open before storms battered the East Coast.

"This is a unique opportunity to reunite the 'House of Calvin Klein' and reinforces our strategy to drive the global growth of Calvin Klein," PVH Chairman and CEO Emanuel Chirico said in a statement.

The combined companies would have more than $8 billion in annual revenue. PVH's other brands include Izod and Arrow.

The deal is expected to close early next year. The boards of directors for both New York-based companies have unanimously approved it.

After it closes, Warnaco shareholders will own about 10 percent of PVH's outstanding common stock. Warnaco CEO Helen McCluskey is expected to join PVH's board of directors.

PVH said it expects the deal to boost earnings in the first full year after it closes, excluding one-time integration costs and transaction expenses.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-10-31-PVH-Warnaco%20Group-Acquisition/id-2905123153164a15a7730880e5852973

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Prescription software developer raises $4.25M for physical

A healthcare IT startup is developing physical rehabilitation software that could be prescribed by doctors or physical therapists.

Reflexion Health has raised $4.25 million from the West Health Investment Fund for its Rehabilitation Tracker program, according to a company statement. It is an affiliate of the West Health Institute founded by telemarketing billionaires Gary and Mary West.

The program uses Microsoft Kinect motion software licensed from the West Health Institute. The Rehabilitation Tracker provides exercises, instructional videos and patient education material that can be set to the needs of each patient. The software allows a physician and physical therapist to track the performance and adherence of their patient.

The concept of prescribing software programs isn?t a new one. New York-based Happtique has been recruiting for a prescription apps pilot program that includes physical therapy as well as areas such as rheumatoid arthritis, diabetes and personal training.

It?s the second of two companies in the La Jolla, California-based West Health Incubator, also affiliated with the West Health Institute. The first was Sense4Baby, a company developing wireless, remote fetal monitoring systems to help obstetricians monitor the health of a mother and baby remotely when a physician isn?t available.

In an interview with Xconomy, Reflexion CEO and co-founder Spencer Hutchins said it will use the funding to advance development of its interactive software. Hutchins said the company wants to explore a marketing approach that would entail enrolling physicians and physical therapists as resellers who would prescribe the program.

Patient adherence is a hot area for providers who are under pressure to reduce readmissions that stem from issues like not following physician instructions or taking medication.

Copyright 2012 MedCity News. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://medcitynews.com/2012/10/prescription-software-developer-raises-4-2m-for-physical-therapy-program-video/

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Thursday, October 11, 2012

Verizon-bound Nokia Lumia 822 surfaces in leaked photos

Verizon-bound Nokia Lumia 822 surfaces in leaked photos

We caught a glimpse of a Verizon-branded Windows Phone 8 handset by the name of Atlas in a leaked image yesterday, and now new photos give us a closer look at the smartphone. According to WMPoweruser, who received the photos from a tipster, the device is a Nokia Lumia 820 variant and will be exclusive to Big Red as the Lumia 822. Though it's riffed on its progenitor's design, the mobile will keep the same WVGA resolution and 8-megapixel rear-facing camera. There's still no official word from Verizon or Nokia regarding the phone, but we expect that to change relatively soon.

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Verizon-bound Nokia Lumia 822 surfaces in leaked photos originally appeared on Engadget on Wed, 10 Oct 2012 19:04:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2012/10/10/verizon-nokia-lumia-822-leaked-pictures/

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Wednesday, October 10, 2012

Fertility discovery a sperm's tail

Tuesday, October 9, 2012

New insights into sperms' swimming skills shed light on male infertility, which affects one in 20 men, and could provide a new avenue to the development of a male contraceptive pill.

In a study published in the journal PLoS Genetics, researchers from Monash University, the University of Newcastle, John Curtin School of Medical Research and Garvan Institute of Medical Research, in Australia; and the University of Cambridge, in the UK, have shown how a protein called RABL2 affects the length of sperm tails, crippling their motility (or swimming ability), and decreases sperm production.

Professor Moira O'Bryan from Monash University's School of Biomedical Sciences (SOBS) led the research. In laboratory tests, the team found that a mutation in RABL2 resulted in sperm tails that were 17 per cent shorter than normal. Dysfunctioning RABL2 also negatively affected sperm production, resulting in a 50 per cent decrease.

Professor O'Bryan said the research fitted another piece in the jigsaw puzzle of sperm development.

"The mutations in the RABL2 gene are very likely to cause infertility," Professor O'Bryan said.

"Further, as motility is absolutely essential for fertility, insights into tail function may reveal options for urgently needed male-based contraception."

Lead author and PhD student Jennifer Lo, also from the School of Biomedical Sciences, said RABL2 worked with other molecules known as intraflagellar transport proteins that carry genetic cargo along the sperm tail.

"Intraflagellar transport proteins are like a train. Our data suggests that the reloading of the train is defective if RABL2 dysfunctions," Ms Lo said.

"The train is still running in sperm tails with dysfunctional RABL2, but it contains fewer passengers. The end result is that sperm formation and motility are abnormal."

Ms Lo said that as mutations in RABL2 decrease sperm count and sperm swimming ability, it may be possible to inhibit this protein in a future male pill.

However, as RABL2 is also found, albeit in lower concentrations, in other tissues, such as the brain, kidney and liver, an inhibitor specific to the testes would need to be developed

Professor O'Bryan said that male infertility was often the canary in the coal mine of general health.

"Many of the basic processes of sperm development occur at lower levels in other organs of the body. As such, the presentation of a man for infertility treatment offers the opportunity not only to give him the children he desires but also to mitigate future disease," Professor O'Bryan said.

###

Monash University: http://www.monash.edu.au

Thanks to Monash University for this article.

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Source: http://www.labspaces.net/124296/Fertility_discovery_a_sperm_s_tail

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Tuesday, October 9, 2012

CoreyNYC: RT @OGTedBerg: Hard to keep watching this playoff baseball game when I can just follow twitter and hear all about your fantasy football ...